Building the synaptonemal complex: Molecular interactions between the axis and the central region.

Building the synaptonemal complex: Molecular interactions between the axis and the central region.

Blog Article

The successful delivery of genetic material to gametes requires tightly regulated interactions between the parental chromosomes.Central to this regulation iphone 14 price miami is a conserved chromosomal interface called the synaptonemal complex (SC), which brings the parental chromosomes in close proximity along their length.While many of its components are known, the interfaces that mediate the assembly of the SC remain a mystery.Here, we survey findings from different model systems while focusing on insight gained in the nematode C.

elegans.We synthesize our read more current understanding of the structure, dynamics, and biophysical properties of the SC and propose mechanisms for SC assembly.